Production of Rh Agglutinins Anti-C and Anti-E

Dextran as a medium for the demonstration of incomplete anti-Rh-agglutinins; preliminary report.

Acute hemolytic transfusion reactions due to multiple alloantibodies including anti-E, anti-c and anti-Jkb.

We report a case of two consecutive episodes of acute hemolytic transfusion reactions (HTRs) due to multiple alloantibodies in a 34-yr-old man who suffered from avascular necrosis of left femoral head. He received five units of packed red blood cells (RBCs) during surgery. Then the transfusion of packed RBCs was required nine days after the surgery because of the unexplained drop in hemoglobin ...

DOUBLE DELAYED HEMOLYTIC TRANSFUSION REACTIONS CAUSED BY MULTIPLE ANTIBODIES, ANTI-C, ANTI-e, ANTI-Jka, AND ANTI-P1

We report a patient who showed delayed hemolytic transfusion reaction (DHTR) twice in two weeks due to multiple antibodies anti-C, -e and -Jka. The patient was a 67-year-old male with liver cirrhosis and hepatoma. The first DHTR was observed on day 7 after transfusion of 6 units of red cells for bleeding from gastric varices. Levels of both LDH and total bilirubin were remarkably increased and ...

Anti-i cold agglutinins in choriocarcinomatosis: trophoblastic i antigen.

The fetal antigen i has been demonstrated by indirect immunofluorescence on cord erythrocytes and placental trophoblast. A patient with disseminated choriocarcinoma developed high-tire anti-i cold agglutinins, and minor elevation of anti-i titres was seen in four out of six further patients with treated choriocarcinoma. In normal pregnant women, 6% showed similar increases in anti-i titres.

Peripheral neuropathy associated with monoclonal IgM anti-Pr2 cold agglutinins.

A patient with a chronic, large fibre sensory neuropathy had an immunoglobulin M lambda monoclonal paraprotein reactive at titres in excess of 1/10(5) with NeuNAc(alpha 2-8)NeuNAc(alpha 2-3)Gal configured disialosyl groups present on the gangliosides GD1b, GT1b, GQ1b, and GD3. The paraprotein showed weaker reactivity with GD1a, GM3, and LM1 but no reactivity with GM2, GM1, or asialo-GM1. In add...